(E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide
TL;DR: (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide (CAS 476319-89-8) is a chemical compound with molecular formula C16H11N3O5S and molecular weight 357.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(2-methyl-1,3-dioxoisoindol-5-yl)-3-(5-nitrothiophen-2-yl)prop-2-enamide
Also Known As: F0463-0203, (E)-N-(2-methyl-1,3-dioxoisoindol-5-yl)-3-(5-nitrothiophen-2-yl)prop-2-enamide, (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide, (2E)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)-3-(5-nitrothiophen-2-yl)prop-2-enamide
| Molecular Formula | C16H11N3O5S |
|---|---|
| Molecular Weight | 357.04 g/mol |
| LogP | 2.534 |
| Topological Polar Surface Area | 109.62 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 357.04193 |
| Heavy Atoms | 25 |
| Complexity | 946.9969 |
Chemical Identifiers
| CAS Number | 476319-89-8 |
|---|---|
| SMILES | CN1C(=O)C2=C(C1=O)C=C(C=C2)NC(=O)/C=C/C3=CC=C(S3)[N+](=O)[O-] |
Product Overview
(E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide (CAS 476319-89-8), with molecular formula C16H11N3O5S and molecular weight 357.04 g/mol. IUPAC: (E)-N-(2-methyl-1,3-dioxoisoindol-5-yl)-3-(5-nitrothiophen-2-yl)prop-2-enamide.
Chemical Property Profile of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide
Property Insights of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide
The XLogP value of 2.534 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide. The TPSA of 109.62 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide. Following Lipinski's Rule of Five, (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide?
The CAS number of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide is 476319-89-8.
What is the molecular formula of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide?
The molecular formula of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide is C16H11N3O5S.
What is the molecular weight of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide?
The molecular weight of (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide is 357.04 g/mol.
Where can I buy (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide?
You can request a quote for (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(2-methyl-1,3-dioxoisoindolin-5-yl)-3-(5-nitrothiophen-2-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.