N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide
TL;DR: N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide (CAS 476308-38-0) is a chemical compound with molecular formula C11H10N2O2S and molecular weight 234.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(5-methyl-1,2-oxazol-3-yl)-3-thiophen-2-ylprop-2-enamide
Also Known As: N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide, (E)-N-(5-methylisoxazol-3-yl)-3-(thiophen-2-yl)acrylamide, (E)-N-(5-methyl-1,2-oxazol-3-yl)-3-thiophen-2-ylprop-2-enamide, F0440-0191, (2E)-N-(5-methyl-1,2-oxazol-3-yl)-3-(thiophen-2-yl)prop-2-enamide
| Molecular Formula | C11H10N2O2S |
|---|---|
| Molecular Weight | 234.05 g/mol |
| LogP | 2.69642 |
| Topological Polar Surface Area | 55.13 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 234.0463 |
| Heavy Atoms | 16 |
| Complexity | 499.79657 |
Chemical Identifiers
| CAS Number | 476308-38-0 |
|---|---|
| SMILES | CC1=CC(=NO1)NC(=O)/C=C/C2=CC=CS2 |
Product Overview
N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide (CAS 476308-38-0), with molecular formula C11H10N2O2S and molecular weight 234.05 g/mol. IUPAC: (E)-N-(5-methyl-1,2-oxazol-3-yl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide
Property Insights of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide
The XLogP value of 2.69642 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide. With a topological polar surface area (TPSA) of 55.13 Ų, N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide?
The CAS number of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide is 476308-38-0.
What is the molecular formula of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide?
The molecular formula of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide is C11H10N2O2S.
What is the molecular weight of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide?
The molecular weight of N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide is 234.05 g/mol.
Where can I buy N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide?
You can request a quote for N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-methyl-3-isoxazolyl)-3-(2-thienyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.