N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide
TL;DR: N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide (CAS 476308-34-6) is a chemical compound with molecular formula C14H11NO3S and molecular weight 273.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(1,3-benzodioxol-5-yl)-3-thiophen-2-ylprop-2-enamide
Also Known As: N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide, F0440-0179, (E)-N-(1,3-benzodioxol-5-yl)-3-thiophen-2-ylprop-2-enamide, (2E)-N-(2H-1,3-BENZODIOXOL-5-YL)-3-(THIOPHEN-2-YL)PROP-2-ENAMIDE, (E)-N-(benzo[d][1,3]dioxol-5-yl)-3-(thiophen-2-yl)acrylamide
| Molecular Formula | C14H11NO3S |
|---|---|
| Molecular Weight | 273.05 g/mol |
| LogP | 3.1287 |
| Topological Polar Surface Area | 47.56 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 273.04596 |
| Heavy Atoms | 19 |
| Complexity | 619.6262 |
Chemical Identifiers
| CAS Number | 476308-34-6 |
|---|---|
| SMILES | C1OC2=C(O1)C=C(C=C2)NC(=O)/C=C/C3=CC=CS3 |
Product Overview
N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide (CAS 476308-34-6), with molecular formula C14H11NO3S and molecular weight 273.05 g/mol. IUPAC: (E)-N-(1,3-benzodioxol-5-yl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide
Property Insights of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide
The XLogP value of 3.1287 indicates that N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.56 Ų, N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide?
The CAS number of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide is 476308-34-6.
What is the molecular formula of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide?
The molecular formula of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide is C14H11NO3S.
What is the molecular weight of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide?
The molecular weight of N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide is 273.05 g/mol.
Where can I buy N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide?
You can request a quote for N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for N-(1,3-benzodioxol-5-yl)-3-(2-thienyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.