N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide
TL;DR: N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide (CAS 476308-31-3) is a chemical compound with molecular formula C14H12N2O4S and molecular weight 304.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(4-methoxy-2-nitrophenyl)-3-thiophen-2-ylprop-2-enamide
Also Known As: N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide, (E)-N-(4-methoxy-2-nitrophenyl)-3-thiophen-2-ylprop-2-enamide, (2E)-N-(4-methoxy-2-nitrophenyl)-3-(2-thienyl)prop-2-enamide, (2E)-N-(4-methoxy-2-nitrophenyl)-3-(thiophen-2-yl)prop-2-enamide
| Molecular Formula | C14H12N2O4S |
|---|---|
| Molecular Weight | 304.05 g/mol |
| LogP | 3.3168 |
| Topological Polar Surface Area | 81.47 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 304.0518 |
| Heavy Atoms | 21 |
| Complexity | 680.28735 |
Chemical Identifiers
| CAS Number | 476308-31-3 |
|---|---|
| SMILES | COC1=CC(=C(C=C1)NC(=O)/C=C/C2=CC=CS2)[N+](=O)[O-] |
Product Overview
N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide (CAS 476308-31-3), with molecular formula C14H12N2O4S and molecular weight 304.05 g/mol. IUPAC: (E)-N-(4-methoxy-2-nitrophenyl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide
Property Insights of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide
The XLogP value of 3.3168 indicates that N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.47 Ų falls within the moderate polarity range, balancing permeability and solubility for N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide. Following Lipinski's Rule of Five, N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide?
The CAS number of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide is 476308-31-3.
What is the molecular formula of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide?
The molecular formula of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide is C14H12N2O4S.
What is the molecular weight of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide?
The molecular weight of N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide is 304.05 g/mol.
Where can I buy N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide?
You can request a quote for N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for N-{2-nitro-4-methoxyphenyl}-3-(2-thienyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.