Methyldihydrocodeine structure

Methyldihydrocodeine

TL;DR: Methyldihydrocodeine (CAS 476-63-1) is a chemical compound with molecular formula C19H25NO3 and molecular weight 315.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(4R,4aR,7S,7aR,12bS)-7,9-dimethoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline

Also Known As: Methyldihydrocodeine, Tetrahydrothebaine, Codeine, methyldihydro-, Magnoflorine Hydroxide, O-METHYLDIHYDROCODEINE

CAS: 476-63-1
Molecular Formula C19H25NO3
Molecular Weight 315.18 g/mol
LogP 2.3792
Topological Polar Surface Area 30.93 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 315.18344
Heavy Atoms 23
Complexity 660.25995

Chemical Identifiers

CAS Number 476-63-1
SMILES CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](CC4)OC

Product Overview

Methyldihydrocodeine (CAS 476-63-1), with molecular formula C19H25NO3 and molecular weight 315.18 g/mol. IUPAC: (4R,4aR,7S,7aR,12bS)-7,9-dimethoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Methyldihydrocodeine

XLogP
2.3792
TPSA (Topological Polar Surface Area)
30.93
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
23
Complexity
660.25995
Exact Mass
315.18344
Monoisotopic Mass
315.18344
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Methyldihydrocodeine

The XLogP value of 2.3792 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Methyldihydrocodeine. With a topological polar surface area (TPSA) of 30.93 Ų, Methyldihydrocodeine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Methyldihydrocodeine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Methyldihydrocodeine?

The CAS number of Methyldihydrocodeine is 476-63-1.

What is the molecular formula of Methyldihydrocodeine?

The molecular formula of Methyldihydrocodeine is C19H25NO3.

What is the molecular weight of Methyldihydrocodeine?

The molecular weight of Methyldihydrocodeine is 315.18 g/mol.

Where can I buy Methyldihydrocodeine?

You can request a quote for Methyldihydrocodeine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Methyldihydrocodeine?

Yes, KEHONG BIO provides custom synthesis services for Methyldihydrocodeine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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