3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide
TL;DR: 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide (CAS 4753-84-8) is a chemical compound with molecular formula C11H7ClF2N2OS and molecular weight 287.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide
Also Known As: 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide
| Molecular Formula | C11H7ClF2N2OS |
|---|---|
| Molecular Weight | 287.99 g/mol |
| LogP | 3.4366 |
| Topological Polar Surface Area | 41.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 287.99356 |
| Heavy Atoms | 18 |
| Complexity | 588.17224 |
Chemical Identifiers
| CAS Number | 4753-84-8 |
|---|---|
| SMILES | C1=CC(=C(C=C1F)F)NNC(=O)C2=C(C=CS2)Cl |
Product Overview
3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide (CAS 4753-84-8), with molecular formula C11H7ClF2N2OS and molecular weight 287.99 g/mol. IUPAC: 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide.
Chemical Property Profile of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide
Property Insights of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide
The XLogP value of 3.4366 indicates that 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.13 Ų, 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide?
The CAS number of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide is 4753-84-8.
What is the molecular formula of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide?
The molecular formula of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide is C11H7ClF2N2OS.
What is the molecular weight of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide?
The molecular weight of 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide is 287.99 g/mol.
Where can I buy 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide?
You can request a quote for 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 3-chloro-N'-(2,4-difluorophenyl)thiophene-2-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.