6alpha-Methyl-9alpha-fluoroprednisolone
TL;DR: 6alpha-Methyl-9alpha-fluoroprednisolone (CAS 475-32-1) is a chemical compound with molecular formula C22H29FO5 and molecular weight 392.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S,8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Also Known As: 9alpha-Fluoro-6alpha-methylprednisolone, 6alpha-methyl-9alpha-fluoroprednisolone, 9?-Fluoro-6?-methylprednisolone, Fluorometholone 21-hydroxy analogue, 6.alpha.-Methyl-9.alpha.-fluoroprednisolone
| Molecular Formula | C22H29FO5 |
|---|---|
| Molecular Weight | 392.20 g/mol |
| LogP | 1.9 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 392.1999 |
| Heavy Atoms | 28 |
| Complexity | 805.0 |
Chemical Identifiers
| CAS Number | 475-32-1 |
|---|---|
| SMILES | C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@]2([C@@]4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)CO)O |
| InChIKey | AWFOJLJWZNBTBX-MJWISQFFSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6alpha-Methyl-9alpha-fluoroprednisolone (CAS 475-32-1), with molecular formula C22H29FO5 and molecular weight 392.20 g/mol. IUPAC: (6S,8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 6alpha-Methyl-9alpha-fluoroprednisolone
Property Insights of 6alpha-Methyl-9alpha-fluoroprednisolone
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6alpha-Methyl-9alpha-fluoroprednisolone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 6alpha-Methyl-9alpha-fluoroprednisolone. Following Lipinski's Rule of Five, 6alpha-Methyl-9alpha-fluoroprednisolone has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6alpha-Methyl-9alpha-fluoroprednisolone?
The CAS number of 6alpha-Methyl-9alpha-fluoroprednisolone is 475-32-1.
What is the molecular formula of 6alpha-Methyl-9alpha-fluoroprednisolone?
The molecular formula of 6alpha-Methyl-9alpha-fluoroprednisolone is C22H29FO5.
What is the molecular weight of 6alpha-Methyl-9alpha-fluoroprednisolone?
The molecular weight of 6alpha-Methyl-9alpha-fluoroprednisolone is 392.20 g/mol.
Where can I buy 6alpha-Methyl-9alpha-fluoroprednisolone?
You can request a quote for 6alpha-Methyl-9alpha-fluoroprednisolone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6alpha-Methyl-9alpha-fluoroprednisolone?
Yes, KEHONG BIO provides custom synthesis services for 6alpha-Methyl-9alpha-fluoroprednisolone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.