(Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide
TL;DR: (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide (CAS 474393-76-5) is a chemical compound with molecular formula C25H23ClN4O3S and molecular weight 494.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide
Also Known As: (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide, N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-[2-(morpholin-4-yl)-4-phenyl-1,3-thiazol-5-yl]prop-2-enamide
| Molecular Formula | C25H23ClN4O3S |
|---|---|
| Molecular Weight | 494.12 g/mol |
| LogP | 5.1628 |
| Topological Polar Surface Area | 87.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 494.11795 |
| Heavy Atoms | 34 |
| Complexity | 1261.1554 |
Chemical Identifiers
| CAS Number | 474393-76-5 |
|---|---|
| SMILES | CC1=CC(=C(C=C1Cl)OC)NC(=O)/C(=C\C2=C(N=C(S2)N3CCOCC3)C4=CC=CC=C4)/C#N |
Product Overview
(Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide (CAS 474393-76-5), with molecular formula C25H23ClN4O3S and molecular weight 494.12 g/mol. IUPAC: (Z)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide.
Chemical Property Profile of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide
Property Insights of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide
The XLogP value of 5.1628 indicates that (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 87.48 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide. Following Lipinski's Rule of Five, (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide?
The CAS number of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide is 474393-76-5.
What is the molecular formula of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide?
The molecular formula of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide is C25H23ClN4O3S.
What is the molecular weight of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide?
The molecular weight of (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide is 494.12 g/mol.
Where can I buy (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide?
You can request a quote for (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-N-(4-Chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(2-morpholin-4-yl-4-phenyl-1,3-thiazol-5-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.