2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine
TL;DR: 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine (CAS 474290-15-8) is a chemical compound with molecular formula C21H16FN3O and molecular weight 345.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine
Also Known As: 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine, AJ-292/41722653, N-[2-(2-fluorophenyl)-4-quinazolinyl]-N-(4-methoxyphenyl)amine
| Molecular Formula | C21H16FN3O |
|---|---|
| Molecular Weight | 345.13 g/mol |
| LogP | 5.1 |
| Topological Polar Surface Area | 47.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 345.12775 |
| Heavy Atoms | 26 |
| Complexity | 443.0 |
Chemical Identifiers
| CAS Number | 474290-15-8 |
|---|---|
| SMILES | COC1=CC=C(C=C1)NC2=NC(=NC3=CC=CC=C32)C4=CC=CC=C4F |
| InChIKey | JGLSGBQGDPXGMM-UHFFFAOYSA-N |
Product Overview
2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine (CAS 474290-15-8), with molecular formula C21H16FN3O and molecular weight 345.13 g/mol. IUPAC: 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine.
Chemical Property Profile of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine
Property Insights of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine
The XLogP value of 5.1 indicates that 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.0 Ų, 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine?
The CAS number of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine is 474290-15-8.
What is the molecular formula of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine?
The molecular formula of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine is C21H16FN3O.
What is the molecular weight of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine?
The molecular weight of 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine is 345.13 g/mol.
Where can I buy 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine?
You can request a quote for 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for 2-(2-fluorophenyl)-N-(4-methoxyphenyl)quinazolin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.