AF-399/13855018 structure

AF-399/13855018

TL;DR: AF-399/13855018 (CAS 474258-00-9) is a chemical compound with molecular formula C14H14F4N2O4 and molecular weight 350.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 6-(3-fluorophenyl)-4-hydroxy-2-oxo-4-(trifluoromethyl)-1,3-diazinane-5-carboxylate

Also Known As: AF-399/13855018, ethyl 6-(3-fluorophenyl)-4-hydroxy-2-oxo-4-(trifluoromethyl)hexahydropyrimidine-5-carboxylate, ethyl 6-(3-fluorophenyl)-4-hydroxy-2-oxo-4-(trifluoromethyl)-1,3-diazinane-5-carboxylate, ethyl 6-(3-fluorophenyl)-4-hydroxy-2-oxo-4-(trifluoromethyl)hexahydro-5-pyrimidinecarboxylate

CAS: 474258-00-9
Molecular Formula C14H14F4N2O4
Molecular Weight 350.09 g/mol
LogP 1.6098
Topological Polar Surface Area 87.66 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 350.08896
Heavy Atoms 24
Complexity 651.90674

Chemical Identifiers

CAS Number 474258-00-9
SMILES CCOC(=O)C1C(NC(=O)NC1(C(F)(F)F)O)C2=CC(=CC=C2)F

Product Overview

AF-399/13855018 (CAS 474258-00-9), with molecular formula C14H14F4N2O4 and molecular weight 350.09 g/mol. IUPAC: ethyl 6-(3-fluorophenyl)-4-hydroxy-2-oxo-4-(trifluoromethyl)-1,3-diazinane-5-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/13855018

XLogP
1.6098
TPSA (Topological Polar Surface Area)
87.66
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
24
Complexity
651.90674
Exact Mass
350.08896
Monoisotopic Mass
350.08896
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/13855018

The XLogP value of 1.6098 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AF-399/13855018. The TPSA of 87.66 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/13855018. Following Lipinski's Rule of Five, AF-399/13855018 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/13855018?

The CAS number of AF-399/13855018 is 474258-00-9.

What is the molecular formula of AF-399/13855018?

The molecular formula of AF-399/13855018 is C14H14F4N2O4.

What is the molecular weight of AF-399/13855018?

The molecular weight of AF-399/13855018 is 350.09 g/mol.

Where can I buy AF-399/13855018?

You can request a quote for AF-399/13855018 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/13855018?

Yes, KEHONG BIO provides custom synthesis services for AF-399/13855018 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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