VU0494018-1
TL;DR: VU0494018-1 (CAS 473567-18-9) is a chemical compound with molecular formula C20H27Cl2FN2O3 and molecular weight 432.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(4-fluorophenyl)piperazin-1-yl]-3-(3-methoxyphenoxy)propan-2-ol;dihydrochloride
Also Known As: VU0494018-1, 1-[4-(4-fluorophenyl)piperazin-1-yl]-3-(3-methoxyphenoxy)propan-2-ol Dihydrochloride, F0840-0011, 1-(4-(4-fluorophenyl)piperazin-1-yl)-3-(3-methoxyphenoxy)propan-2-ol dihydrochloride, 1-[4-(4-fluorophenyl)piperazin-1-yl]-3-(3-methoxyphenoxy)propan-2-ol;dihydrochloride
| Molecular Formula | C20H27Cl2FN2O3 |
|---|---|
| Molecular Weight | 432.14 g/mol |
| LogP | 3.2398 |
| Topological Polar Surface Area | 45.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 432.13828 |
| Heavy Atoms | 28 |
| Complexity | 698.1051 |
Chemical Identifiers
| CAS Number | 473567-18-9 |
|---|---|
| SMILES | COC1=CC(=CC=C1)OCC(CN2CCN(CC2)C3=CC=C(C=C3)F)O.Cl.Cl |
Product Overview
VU0494018-1 (CAS 473567-18-9), with molecular formula C20H27Cl2FN2O3 and molecular weight 432.14 g/mol. IUPAC: 1-[4-(4-fluorophenyl)piperazin-1-yl]-3-(3-methoxyphenoxy)propan-2-ol;dihydrochloride.
Chemical Property Profile of VU0494018-1
Property Insights of VU0494018-1
The XLogP value of 3.2398 indicates that VU0494018-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.17 Ų, VU0494018-1 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, VU0494018-1 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of VU0494018-1?
The CAS number of VU0494018-1 is 473567-18-9.
What is the molecular formula of VU0494018-1?
The molecular formula of VU0494018-1 is C20H27Cl2FN2O3.
What is the molecular weight of VU0494018-1?
The molecular weight of VU0494018-1 is 432.14 g/mol.
Where can I buy VU0494018-1?
You can request a quote for VU0494018-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for VU0494018-1?
Yes, KEHONG BIO provides custom synthesis services for VU0494018-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.