NPE607
TL;DR: NPE607 (CAS 473446-65-0) is a chemical compound with molecular formula C21H24N2O3S and molecular weight 384.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[[4-(4-propan-2-ylphenyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid
Also Known As: NPE607, BIM-0019730.P001, 2-[[4-(4-propan-2-ylphenyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-3-carboxylic acid, 3-({[4-(4-isopropylphenyl)-1,3-thiazol-2-yl]amino}carbonyl)bicyclo[2.2.1]heptane-2-carboxylic acid, 3-({4-[4-(propan-2-yl)phenyl]-1,3-thiazol-2-yl}carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid
| Molecular Formula | C21H24N2O3S |
|---|---|
| Molecular Weight | 384.15 g/mol |
| LogP | 4.6189 |
| Topological Polar Surface Area | 79.29 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 384.15076 |
| Heavy Atoms | 27 |
| Complexity | 858.5666 |
Chemical Identifiers
| CAS Number | 473446-65-0 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3C4CCC(C4)C3C(=O)O |
Product Overview
NPE607 (CAS 473446-65-0), with molecular formula C21H24N2O3S and molecular weight 384.15 g/mol. IUPAC: 3-[[4-(4-propan-2-ylphenyl)-1,3-thiazol-2-yl]carbamoyl]bicyclo[2.2.1]heptane-2-carboxylic acid.
Chemical Property Profile of NPE607
Property Insights of NPE607
The XLogP value of 4.6189 indicates that NPE607 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.29 Ų falls within the moderate polarity range, balancing permeability and solubility for NPE607. Following Lipinski's Rule of Five, NPE607 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of NPE607?
The CAS number of NPE607 is 473446-65-0.
What is the molecular formula of NPE607?
The molecular formula of NPE607 is C21H24N2O3S.
What is the molecular weight of NPE607?
The molecular weight of NPE607 is 384.15 g/mol.
Where can I buy NPE607?
You can request a quote for NPE607 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for NPE607?
Yes, KEHONG BIO provides custom synthesis services for NPE607 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.