Meclorisone
TL;DR: Meclorisone (CAS 4732-48-3) is a chemical compound with molecular formula C22H28Cl2O4 and molecular weight 426.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9R,10S,11S,13S,14S,16R,17R)-9,11-dichloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Also Known As: Meclorisone, Meclorisona, Meclorisonum, Meclorisone [INN:BAN], Meclorisonum [INN-Latin]
| Molecular Formula | C22H28Cl2O4 |
|---|---|
| Molecular Weight | 426.14 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 426.13647 |
| Heavy Atoms | 28 |
| Complexity | 806.0 |
Chemical Identifiers
| CAS Number | 4732-48-3 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)Cl)Cl)C |
| InChIKey | OKWSMPYQIYKVDC-CXSFZGCWSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Meclorisone (CAS 4732-48-3), with molecular formula C22H28Cl2O4 and molecular weight 426.14 g/mol. IUPAC: (8S,9R,10S,11S,13S,14S,16R,17R)-9,11-dichloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of Meclorisone
Property Insights of Meclorisone
The XLogP value of 3.5 indicates that Meclorisone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Meclorisone. Following Lipinski's Rule of Five, Meclorisone has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Meclorisone?
The CAS number of Meclorisone is 4732-48-3.
What is the molecular formula of Meclorisone?
The molecular formula of Meclorisone is C22H28Cl2O4.
What is the molecular weight of Meclorisone?
The molecular weight of Meclorisone is 426.14 g/mol.
Where can I buy Meclorisone?
You can request a quote for Meclorisone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Meclorisone?
Yes, KEHONG BIO provides custom synthesis services for Meclorisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.