progesterone, 9,21-difluoro-11
TL;DR: progesterone, 9,21-difluoro-11 (CAS 472-24-2) is a chemical compound with molecular formula C21H28F2O4 and molecular weight 382.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-17-(2-fluoroacetyl)-11,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Also Known As: progesterone, 9,21-difluoro-11, A,17-dihydroxy-, Progesterone,21-difluoro-11.beta.,17-dihydroxy-, Pregn-4-ene-3, 9,21-difluoro-11.beta.,17-dihydroxy-, (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-17-(2-fluoroacetyl)-11,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
| Molecular Formula | C21H28F2O4 |
|---|---|
| Molecular Weight | 382.20 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 382.19556 |
| Heavy Atoms | 27 |
| Complexity | 736.0 |
Chemical Identifiers
| CAS Number | 472-24-2 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CF)O)C)O)F |
| InChIKey | HMQHDCRSYKWXAA-BULBTXNYSA-N |
Product Overview
progesterone, 9,21-difluoro-11 (CAS 472-24-2), with molecular formula C21H28F2O4 and molecular weight 382.20 g/mol. IUPAC: (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-17-(2-fluoroacetyl)-11,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of progesterone, 9,21-difluoro-11
Property Insights of progesterone, 9,21-difluoro-11
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for progesterone, 9,21-difluoro-11. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for progesterone, 9,21-difluoro-11. Following Lipinski's Rule of Five, progesterone, 9,21-difluoro-11 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of progesterone, 9,21-difluoro-11?
The CAS number of progesterone, 9,21-difluoro-11 is 472-24-2.
What is the molecular formula of progesterone, 9,21-difluoro-11?
The molecular formula of progesterone, 9,21-difluoro-11 is C21H28F2O4.
What is the molecular weight of progesterone, 9,21-difluoro-11?
The molecular weight of progesterone, 9,21-difluoro-11 is 382.20 g/mol.
Where can I buy progesterone, 9,21-difluoro-11?
You can request a quote for progesterone, 9,21-difluoro-11 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for progesterone, 9,21-difluoro-11?
Yes, KEHONG BIO provides custom synthesis services for progesterone, 9,21-difluoro-11 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.