Pioglitazone Didehydro Hydroxy Impurity structure

Pioglitazone Didehydro Hydroxy Impurity

TL;DR: Pioglitazone Didehydro Hydroxy Impurity (CAS 471295-99-5) is a chemical compound with molecular formula C19H18N2O4S and molecular weight 370.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(5E)-5-[[4-[2-(5-ethyl-2-pyridinyl)-2-hydroxyethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione

Also Known As: Pioglitazone Didehydro Hydroxy Impurity, (E)-5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzylidene)thiazolidine-2,4-dione, (Z)-5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzylidene)thiazolidine-2,4-dione, 5-{4-[2-(5-Ethyl-2-pyridinyl) 2-hydroxyethoxy] benzylidene}-2,4-thiazolidinedione, (5Z)-5-({4-[2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione

CAS: 471295-99-5
Molecular Formula C19H18N2O4S
Molecular Weight 370.10 g/mol
LogP 3.0803
Topological Polar Surface Area 88.52 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 370.09872
Heavy Atoms 26
Complexity 831.62256

Chemical Identifiers

CAS Number 471295-99-5
SMILES CCC1=CN=C(C=C1)C(COC2=CC=C(C=C2)/C=C/3\C(=O)NC(=O)S3)O

Product Overview

Pioglitazone Didehydro Hydroxy Impurity (CAS 471295-99-5), with molecular formula C19H18N2O4S and molecular weight 370.10 g/mol. IUPAC: (5E)-5-[[4-[2-(5-ethyl-2-pyridinyl)-2-hydroxyethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Pioglitazone Didehydro Hydroxy Impurity

XLogP
3.0803
TPSA (Topological Polar Surface Area)
88.52
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
26
Complexity
831.62256
Exact Mass
370.09872
Monoisotopic Mass
370.09872
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pioglitazone Didehydro Hydroxy Impurity

The XLogP value of 3.0803 indicates that Pioglitazone Didehydro Hydroxy Impurity is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.52 Ų falls within the moderate polarity range, balancing permeability and solubility for Pioglitazone Didehydro Hydroxy Impurity. Following Lipinski's Rule of Five, Pioglitazone Didehydro Hydroxy Impurity has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pioglitazone Didehydro Hydroxy Impurity?

The CAS number of Pioglitazone Didehydro Hydroxy Impurity is 471295-99-5.

What is the molecular formula of Pioglitazone Didehydro Hydroxy Impurity?

The molecular formula of Pioglitazone Didehydro Hydroxy Impurity is C19H18N2O4S.

What is the molecular weight of Pioglitazone Didehydro Hydroxy Impurity?

The molecular weight of Pioglitazone Didehydro Hydroxy Impurity is 370.10 g/mol.

Where can I buy Pioglitazone Didehydro Hydroxy Impurity?

You can request a quote for Pioglitazone Didehydro Hydroxy Impurity directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pioglitazone Didehydro Hydroxy Impurity?

Yes, KEHONG BIO provides custom synthesis services for Pioglitazone Didehydro Hydroxy Impurity and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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