(E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide
TL;DR: (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide (CAS 469870-91-5) is a chemical compound with molecular formula C20H12BrCl2N3OS and molecular weight 490.93 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[5-[(4-bromophenyl)methyl]-1,3-thiazol-2-yl]-2-cyano-3-(2,4-dichlorophenyl)prop-2-enamide
Also Known As: (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide, (2E)-3-(2,4-dichlorophenyl)-N-{5-[(4-bromophenyl)methyl](1,3-thiazol-2-yl)}-2- cyanoprop-2-enamide, (2E)-N-[5-(4-bromobenzyl)-1,3-thiazol-2-yl]-2-cyano-3-(2,4-dichlorophenyl)prop-2-enamide, (E)-N-[5-[(4-bromophenyl)methyl]-1,3-thiazol-2-yl]-2-cyano-3-(2,4-dichlorophenyl)prop-2-enamide
| Molecular Formula | C20H12BrCl2N3OS |
|---|---|
| Molecular Weight | 490.93 g/mol |
| LogP | 6.34888 |
| Topological Polar Surface Area | 65.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 490.92615 |
| Heavy Atoms | 28 |
| Complexity | 1087.5754 |
Chemical Identifiers
| CAS Number | 469870-91-5 |
|---|---|
| SMILES | C1=CC(=CC=C1CC2=CN=C(S2)NC(=O)/C(=C/C3=C(C=C(C=C3)Cl)Cl)/C#N)Br |
Product Overview
(E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide (CAS 469870-91-5), with molecular formula C20H12BrCl2N3OS and molecular weight 490.93 g/mol. IUPAC: (E)-N-[5-[(4-bromophenyl)methyl]-1,3-thiazol-2-yl]-2-cyano-3-(2,4-dichlorophenyl)prop-2-enamide.
Chemical Property Profile of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide
Property Insights of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide
The XLogP value of 6.34888 indicates that (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.78 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide. Following Lipinski's Rule of Five, (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide?
The CAS number of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide is 469870-91-5.
What is the molecular formula of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide?
The molecular formula of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide is C20H12BrCl2N3OS.
What is the molecular weight of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide?
The molecular weight of (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide is 490.93 g/mol.
Where can I buy (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide?
You can request a quote for (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(5-(4-bromobenzyl)thiazol-2-yl)-2-cyano-3-(2,4-dichlorophenyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.