(Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate
TL;DR: (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate (CAS 469869-75-8) is a chemical compound with molecular formula C17H14ClN3O3S and molecular weight 375.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 2-[[(Z)-3-(4-chlorophenyl)-2-cyanoprop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
Also Known As: (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate, ethyl (2E)-2-{[(2Z)-3-(4-chlorophenyl)-2-cyanoprop-2-enoyl]imino}-4-methyl-2,3-dihydro-1,3-thiazole-5-carboxylate, ethyl 2-[(2Z)-3-(4-chlorophenyl)-2-cyanoprop-2-enoylamino]-4-methyl-1,3-thiazo le-5-carboxylate, ethyl 2-[[(Z)-3-(4-chlorophenyl)-2-cyanoprop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
| Molecular Formula | C17H14ClN3O3S |
|---|---|
| Molecular Weight | 375.04 g/mol |
| LogP | 3.8273 |
| Topological Polar Surface Area | 92.08 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 375.04443 |
| Heavy Atoms | 25 |
| Complexity | 866.2535 |
Chemical Identifiers
| CAS Number | 469869-75-8 |
|---|---|
| SMILES | CCOC(=O)C1=C(N=C(S1)NC(=O)/C(=C\C2=CC=C(C=C2)Cl)/C#N)C |
Product Overview
(Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate (CAS 469869-75-8), with molecular formula C17H14ClN3O3S and molecular weight 375.04 g/mol. IUPAC: ethyl 2-[[(Z)-3-(4-chlorophenyl)-2-cyanoprop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate.
Chemical Property Profile of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate
Property Insights of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate
The XLogP value of 3.8273 indicates that (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 92.08 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate. Following Lipinski's Rule of Five, (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate?
The CAS number of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate is 469869-75-8.
What is the molecular formula of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate?
The molecular formula of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate is C17H14ClN3O3S.
What is the molecular weight of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate?
The molecular weight of (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate is 375.04 g/mol.
Where can I buy (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate?
You can request a quote for (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (Z)-ethyl 2-(3-(4-chlorophenyl)-2-cyanoacrylamido)-4-methylthiazole-5-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.