14alpha-Artebufogenin
TL;DR: 14alpha-Artebufogenin (CAS 468-86-0) is a chemical compound with molecular formula C24H32O4 and molecular weight 384.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(3-hydroxy-10,13-dimethyl-15-oxo-1,2,3,4,5,6,7,8,9,11,12,14,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl)pyran-2-one
Also Known As: 14alpha-Artebufogenin, 14.alpha.-Artebufogenin, 3-Hydroxy-15-oxobufa-20,22-dienolide, 3-Hydroxy-15-oxobufa-20,22-dienolide #, 5.beta.,22-dienolide, 3.beta.-hydroxy-15-oxo-
| Molecular Formula | C24H32O4 |
|---|---|
| Molecular Weight | 384.23 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 63.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 384.23007 |
| Heavy Atoms | 28 |
| Complexity | 767.0 |
Chemical Identifiers
| CAS Number | 468-86-0 |
|---|---|
| SMILES | CC12CCC(CC1CCC3C2CCC4(C3C(=O)CC4C5=COC(=O)C=C5)C)O |
| InChIKey | NTLOERPHSXBROY-UHFFFAOYSA-N |
Product Overview
14alpha-Artebufogenin (CAS 468-86-0), with molecular formula C24H32O4 and molecular weight 384.23 g/mol. IUPAC: 5-(3-hydroxy-10,13-dimethyl-15-oxo-1,2,3,4,5,6,7,8,9,11,12,14,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl)pyran-2-one.
Chemical Property Profile of 14alpha-Artebufogenin
Property Insights of 14alpha-Artebufogenin
The XLogP value of 3.9 indicates that 14alpha-Artebufogenin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 14alpha-Artebufogenin. Following Lipinski's Rule of Five, 14alpha-Artebufogenin has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 14alpha-Artebufogenin?
The CAS number of 14alpha-Artebufogenin is 468-86-0.
What is the molecular formula of 14alpha-Artebufogenin?
The molecular formula of 14alpha-Artebufogenin is C24H32O4.
What is the molecular weight of 14alpha-Artebufogenin?
The molecular weight of 14alpha-Artebufogenin is 384.23 g/mol.
Where can I buy 14alpha-Artebufogenin?
You can request a quote for 14alpha-Artebufogenin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 14alpha-Artebufogenin?
Yes, KEHONG BIO provides custom synthesis services for 14alpha-Artebufogenin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.