(2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide
TL;DR: (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide (CAS 466654-35-3) is a chemical compound with molecular formula C15H13N3O2S and molecular weight 299.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-cyano-3-(4-ethoxyphenyl)-N-(1,3-thiazol-2-yl)prop-2-enamide
Also Known As: (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide, 2-cyano-3-(4-ethoxyphenyl)-N-(1,3-thiazol-2-yl)prop-2-enamide
| Molecular Formula | C15H13N3O2S |
|---|---|
| Molecular Weight | 299.07 g/mol |
| LogP | 3.08748 |
| Topological Polar Surface Area | 75.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 299.07285 |
| Heavy Atoms | 21 |
| Complexity | 669.94434 |
Chemical Identifiers
| CAS Number | 466654-35-3 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)C=C(C#N)C(=O)NC2=NC=CS2 |
Product Overview
(2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide (CAS 466654-35-3), with molecular formula C15H13N3O2S and molecular weight 299.07 g/mol. IUPAC: 2-cyano-3-(4-ethoxyphenyl)-N-(1,3-thiazol-2-yl)prop-2-enamide.
Chemical Property Profile of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide
Property Insights of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide
The XLogP value of 3.08748 indicates that (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.01 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide. Following Lipinski's Rule of Five, (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide?
The CAS number of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide is 466654-35-3.
What is the molecular formula of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide?
The molecular formula of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide is C15H13N3O2S.
What is the molecular weight of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide?
The molecular weight of (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide is 299.07 g/mol.
Where can I buy (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide?
You can request a quote for (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-2-cyano-3-(4-ethoxyphenyl)-N-1,3-thiazol-2-ylacrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.