![N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide structure](/static/products/4655/465510-56-9.webp)
N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide
TL;DR: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide (CAS 465510-56-9) is a chemical compound with molecular formula C18H12ClF3N2O3 and molecular weight 396.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide
Also Known As: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide, (E)-N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide
| Molecular Formula | C18H12ClF3N2O3 |
|---|---|
| Molecular Weight | 396.05 g/mol |
| LogP | 4.61868 |
| Topological Polar Surface Area | 82.35 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 396.04886 |
| Heavy Atoms | 27 |
| Complexity | 949.8436 |
Chemical Identifiers
| CAS Number | 465510-56-9 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)/C=C(\C#N)/C(=O)NC2=C(C=CC(=C2)C(F)(F)F)Cl)O |
Product Overview
N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide (CAS 465510-56-9), with molecular formula C18H12ClF3N2O3 and molecular weight 396.05 g/mol. IUPAC: (E)-N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide.
Chemical Property Profile of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide
Property Insights of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide
The XLogP value of 4.61868 indicates that N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.35 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide. Following Lipinski's Rule of Five, N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide?
The CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide is 465510-56-9.
What is the molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide?
The molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide is C18H12ClF3N2O3.
What is the molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide?
The molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide is 396.05 g/mol.
Where can I buy N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide?
You can request a quote for N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for N-[2-chloro-5-(trifluoromethyl)phenyl]-2-cyano-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.