Thr-Pro structure

Thr-Pro

TL;DR: Thr-Pro (CAS 46398-79-2) is a chemical compound with molecular formula C9H16N2O4 and molecular weight 216.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid

Also Known As: Thr-Pro, H-THR-PRO-OH, threonylproline, L-threonyl-L-proline, threonyl-proline

CAS: 46398-79-2
Molecular Formula C9H16N2O4
Molecular Weight 216.11 g/mol
LogP -1.2299
Topological Polar Surface Area 103.86 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 216.11101
Heavy Atoms 15
Complexity 266.83795

Chemical Identifiers

CAS Number 46398-79-2
SMILES C[C@H]([C@@H](C(=O)N1CCC[C@H]1C(=O)O)N)O

Product Overview

Thr-Pro (CAS 46398-79-2), with molecular formula C9H16N2O4 and molecular weight 216.11 g/mol. IUPAC: (2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thr-Pro

XLogP
-1.2299
TPSA (Topological Polar Surface Area)
103.86
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
15
Complexity
266.83795
Exact Mass
216.11101
Monoisotopic Mass
216.11101
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thr-Pro

The XLogP value of -1.2299 indicates that Thr-Pro is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 103.86 Ų falls within the moderate polarity range, balancing permeability and solubility for Thr-Pro. Following Lipinski's Rule of Five, Thr-Pro has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thr-Pro?

The CAS number of Thr-Pro is 46398-79-2.

What is the molecular formula of Thr-Pro?

The molecular formula of Thr-Pro is C9H16N2O4.

What is the molecular weight of Thr-Pro?

The molecular weight of Thr-Pro is 216.11 g/mol.

Where can I buy Thr-Pro?

You can request a quote for Thr-Pro directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thr-Pro?

Yes, KEHONG BIO provides custom synthesis services for Thr-Pro and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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