1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
TL;DR: 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine (CAS 462063-95-2) is a chemical compound with molecular formula C20H23FN2O4 and molecular weight 374.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(2-fluorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
Also Known As: 1-(2-fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine, AP-263/13033165, [4-(2-fluorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone, 4-(2-fluorophenyl)piperazinyl 3,4,5-trimethoxyphenyl ketone, [4-(2-fluorophenyl)piperazin-1-yl](3,4,5-trimethoxyphenyl)methanone
| Molecular Formula | C20H23FN2O4 |
|---|---|
| Molecular Weight | 374.16 g/mol |
| LogP | 2.8139 |
| Topological Polar Surface Area | 51.24 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 374.16418 |
| Heavy Atoms | 27 |
| Complexity | 794.37415 |
Chemical Identifiers
| CAS Number | 462063-95-2 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)C(=O)N2CCN(CC2)C3=CC=CC=C3F |
Product Overview
1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine (CAS 462063-95-2), with molecular formula C20H23FN2O4 and molecular weight 374.16 g/mol. IUPAC: [4-(2-fluorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone.
Chemical Property Profile of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
Property Insights of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
The XLogP value of 2.8139 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine. With a topological polar surface area (TPSA) of 51.24 Ų, 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine?
The CAS number of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine is 462063-95-2.
What is the molecular formula of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine?
The molecular formula of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine is C20H23FN2O4.
What is the molecular weight of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine?
The molecular weight of 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine is 374.16 g/mol.
Where can I buy 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine?
You can request a quote for 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-(2-Fluorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.