![N-[4-amino-2-(trifluoromethyl)phenyl]acetamide structure](/static/products/4618/461-81-4.webp)
N-[4-amino-2-(trifluoromethyl)phenyl]acetamide
TL;DR: N-[4-amino-2-(trifluoromethyl)phenyl]acetamide (CAS 461-81-4) is a chemical compound with molecular formula C9H9F3N2O and molecular weight 218.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-amino-2-(trifluoromethyl)phenyl]acetamide
Also Known As: 4-Amino-2-(trifluoromethyl)acetanilide, N-[4-amino-2-(trifluoromethyl)phenyl]acetamide, 4'-Amino-2'-(trifluoromethyl)acetanilide, N-(4-amino-2-(trifluoromethyl)phenyl)acetamide, 3868AD
| Molecular Formula | C9H9F3N2O |
|---|---|
| Molecular Weight | 218.07 g/mol |
| LogP | 2.246 |
| Topological Polar Surface Area | 55.12 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 218.0667 |
| Heavy Atoms | 15 |
| Complexity | 387.4341 |
Chemical Identifiers
| CAS Number | 461-81-4 |
|---|---|
| SMILES | CC(=O)NC1=C(C=C(C=C1)N)C(F)(F)F |
Product Overview
N-[4-amino-2-(trifluoromethyl)phenyl]acetamide (CAS 461-81-4), with molecular formula C9H9F3N2O and molecular weight 218.07 g/mol. IUPAC: N-[4-amino-2-(trifluoromethyl)phenyl]acetamide.
Chemical Property Profile of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide
Property Insights of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide
The XLogP value of 2.246 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-[4-amino-2-(trifluoromethyl)phenyl]acetamide. With a topological polar surface area (TPSA) of 55.12 Ų, N-[4-amino-2-(trifluoromethyl)phenyl]acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[4-amino-2-(trifluoromethyl)phenyl]acetamide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide?
The CAS number of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide is 461-81-4.
What is the molecular formula of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide?
The molecular formula of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide is C9H9F3N2O.
What is the molecular weight of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide?
The molecular weight of N-[4-amino-2-(trifluoromethyl)phenyl]acetamide is 218.07 g/mol.
Where can I buy N-[4-amino-2-(trifluoromethyl)phenyl]acetamide?
You can request a quote for N-[4-amino-2-(trifluoromethyl)phenyl]acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[4-amino-2-(trifluoromethyl)phenyl]acetamide?
Yes, KEHONG BIO provides custom synthesis services for N-[4-amino-2-(trifluoromethyl)phenyl]acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.