![8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one structure](/static/products/460/460345-45-3.png)
8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one
TL;DR: 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one (CAS 460345-45-3) is a chemical compound with molecular formula C13H15ClN2O and molecular weight 250.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chlorospiro[1,3-dihydroquinazoline-4,1'-cyclohexane]-2-one
Also Known As: 8'-chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one, 8-chloro-1h-spiro[quinazoline-4,1'-cyclohexane]-2(3h)-one, 8-chlorospiro[1,3-dihydroquinazoline-4,1'-cyclohexane]-2-one, 8''''-chlorospiro[cyclohexane-1,4''''-(1'''',2'''',3'''',4''''-tetrahydroquinazoline)]-2''''-one
| Molecular Formula | C13H15ClN2O |
|---|---|
| Molecular Weight | 250.09 g/mol |
| LogP | 3.6345 |
| Topological Polar Surface Area | 41.13 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 250.0873 |
| Heavy Atoms | 17 |
| Complexity | 466.4873 |
Chemical Identifiers
| CAS Number | 460345-45-3 |
|---|---|
| SMILES | C1CCC2(CC1)C3=C(C(=CC=C3)Cl)NC(=O)N2 |
Product Overview
8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one (CAS 460345-45-3), with molecular formula C13H15ClN2O and molecular weight 250.09 g/mol. IUPAC: 8-chlorospiro[1,3-dihydroquinazoline-4,1'-cyclohexane]-2-one.
Chemical Property Profile of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one
Property Insights of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one
The XLogP value of 3.6345 indicates that 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.13 Ų, 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one?
The CAS number of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one is 460345-45-3.
What is the molecular formula of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one?
The molecular formula of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one is C13H15ClN2O.
What is the molecular weight of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one?
The molecular weight of 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one is 250.09 g/mol.
Where can I buy 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one?
You can request a quote for 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one?
Yes, KEHONG BIO provides custom synthesis services for 8'-Chloro-1'h-spiro[cyclohexane-1,4'-quinazolin]-2'(3'h)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.