F1222-0466
TL;DR: F1222-0466 (CAS 459199-16-7) is a chemical compound with molecular formula C20H20ClN3OS and molecular weight 385.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-chlorophenyl)-N-(3,5-dimethylphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
Also Known As: F1222-0466, 4-(4-chlorophenyl)-N-(3,5-dimethylphenyl)-6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxamide, 4-(4-chlorophenyl)-N-(3,5-dimethylphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide, 4-(4-chlorophenyl)-N-(3,5-dimethylphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
| Molecular Formula | C20H20ClN3OS |
|---|---|
| Molecular Weight | 385.10 g/mol |
| LogP | 4.38834 |
| Topological Polar Surface Area | 53.16 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 385.10156 |
| Heavy Atoms | 26 |
| Complexity | 885.52234 |
Chemical Identifiers
| CAS Number | 459199-16-7 |
|---|---|
| SMILES | CC1=CC(=CC(=C1)NC(=O)C2=C(NC(=S)NC2C3=CC=C(C=C3)Cl)C)C |
Product Overview
F1222-0466 (CAS 459199-16-7), with molecular formula C20H20ClN3OS and molecular weight 385.10 g/mol. IUPAC: 4-(4-chlorophenyl)-N-(3,5-dimethylphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide.
Chemical Property Profile of F1222-0466
Property Insights of F1222-0466
The XLogP value of 4.38834 indicates that F1222-0466 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.16 Ų, F1222-0466 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1222-0466 has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1222-0466?
The CAS number of F1222-0466 is 459199-16-7.
What is the molecular formula of F1222-0466?
The molecular formula of F1222-0466 is C20H20ClN3OS.
What is the molecular weight of F1222-0466?
The molecular weight of F1222-0466 is 385.10 g/mol.
Where can I buy F1222-0466?
You can request a quote for F1222-0466 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1222-0466?
Yes, KEHONG BIO provides custom synthesis services for F1222-0466 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.