JNJ 7777120 structure

JNJ 7777120

TL;DR: JNJ 7777120 (CAS 459168-51-5) is a chemical compound with molecular formula C14H16ClN3O and molecular weight 277.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone

Also Known As: JNJ 7777120, (5-chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone, 1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine, (5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone, [3H]-JNJ7777120

CAS: 459168-51-5
Molecular Formula C14H16ClN3O
Molecular Weight 277.10 g/mol
LogP 2.2089
Topological Polar Surface Area 39.34 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 277.09818
Heavy Atoms 19
Complexity 614.17865

Chemical Identifiers

CAS Number 459168-51-5
SMILES CN1CCN(CC1)C(=O)C2=CC3=C(N2)C=CC(=C3)Cl

Product Overview

JNJ 7777120 (CAS 459168-51-5), with molecular formula C14H16ClN3O and molecular weight 277.10 g/mol. IUPAC: (5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of JNJ 7777120

XLogP
2.2089
TPSA (Topological Polar Surface Area)
39.34
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
19
Complexity
614.17865
Exact Mass
277.09818
Monoisotopic Mass
277.09818
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of JNJ 7777120

The XLogP value of 2.2089 suggests moderate lipophilicity, balancing water solubility and membrane permeability for JNJ 7777120. With a topological polar surface area (TPSA) of 39.34 Ų, JNJ 7777120 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, JNJ 7777120 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of JNJ 7777120?

The CAS number of JNJ 7777120 is 459168-51-5.

What is the molecular formula of JNJ 7777120?

The molecular formula of JNJ 7777120 is C14H16ClN3O.

What is the molecular weight of JNJ 7777120?

The molecular weight of JNJ 7777120 is 277.10 g/mol.

Where can I buy JNJ 7777120?

You can request a quote for JNJ 7777120 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for JNJ 7777120?

Yes, KEHONG BIO provides custom synthesis services for JNJ 7777120 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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