AF-399/40756975 structure

AF-399/40756975

TL;DR: AF-399/40756975 (CAS 459155-79-4) is a chemical compound with molecular formula C18H23F3N2O7 and molecular weight 436.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 6-hydroxy-1-methyl-2-oxo-6-(trifluoromethyl)-4-(3,4,5-trimethoxyphenyl)-1,3-diazinane-5-carboxylate

Also Known As: AF-399/40756975, ethyl 6-hydroxy-1-methyl-2-oxo-6-(trifluoromethyl)-4-(3,4,5-trimethoxyphenyl)-1,3-diazinane-5-carboxylate, ethyl 6-hydroxy-1-methyl-2-oxo-6-(trifluoromethyl)-4-(3,4,5-trimethoxyphenyl)hexahydro-5-pyrimidinecarboxylate, ethyl 6-hydroxy-1-methyl-2-oxo-6-(trifluoromethyl)-4-(3,4,5-trimethoxyphenyl)hexahydropyrimidine-5-carboxylate

CAS: 459155-79-4
Molecular Formula C18H23F3N2O7
Molecular Weight 436.15 g/mol
LogP 1.8387
Topological Polar Surface Area 106.56 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 6
Exact Mass 436.14572
Heavy Atoms 30
Complexity 792.45514

Chemical Identifiers

CAS Number 459155-79-4
SMILES CCOC(=O)C1C(NC(=O)N(C1(C(F)(F)F)O)C)C2=CC(=C(C(=C2)OC)OC)OC

Product Overview

AF-399/40756975 (CAS 459155-79-4), with molecular formula C18H23F3N2O7 and molecular weight 436.15 g/mol. IUPAC: ethyl 6-hydroxy-1-methyl-2-oxo-6-(trifluoromethyl)-4-(3,4,5-trimethoxyphenyl)-1,3-diazinane-5-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/40756975

XLogP
1.8387
TPSA (Topological Polar Surface Area)
106.56
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
6
Heavy Atoms
30
Complexity
792.45514
Exact Mass
436.14572
Monoisotopic Mass
436.14572
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/40756975

The XLogP value of 1.8387 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AF-399/40756975. The TPSA of 106.56 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/40756975. Following Lipinski's Rule of Five, AF-399/40756975 has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/40756975?

The CAS number of AF-399/40756975 is 459155-79-4.

What is the molecular formula of AF-399/40756975?

The molecular formula of AF-399/40756975 is C18H23F3N2O7.

What is the molecular weight of AF-399/40756975?

The molecular weight of AF-399/40756975 is 436.15 g/mol.

Where can I buy AF-399/40756975?

You can request a quote for AF-399/40756975 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/40756975?

Yes, KEHONG BIO provides custom synthesis services for AF-399/40756975 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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