AM-807/14146117
TL;DR: AM-807/14146117 (CAS 459155-75-0) is a chemical compound with molecular formula C25H27N5O4 and molecular weight 461.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
tert-butyl (8R,8aR)-6-amino-5,7,7-tricyano-8-(2,5-dimethoxyphenyl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate
Also Known As: AM-807/14146117, (8R,8aR)-tert-butyl 6-amino-5,7,7-tricyano-8-(2,5-dimethoxyphenyl)-1,7,8,8a-tetrahydroisoquinoline-2(3H)-carboxylate, tert-butyl (8R,8aR)-6-amino-5,7,7-tricyano-8-(2,5-dimethoxyphenyl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate, tert-butyl 6-amino-5,7,7-tricyano-8-(2,5-dimethoxyphenyl)-3,7,8,8a-tetrahydro-2(1H)-isoquinolinecarboxylate
| Molecular Formula | C25H27N5O4 |
|---|---|
| Molecular Weight | 461.21 g/mol |
| LogP | 3.36424 |
| Topological Polar Surface Area | 145.39 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 3 |
| Exact Mass | 461.2063 |
| Heavy Atoms | 34 |
| Complexity | 1175.6188 |
Chemical Identifiers
| CAS Number | 459155-75-0 |
|---|---|
| SMILES | CC(C)(C)OC(=O)N1CC=C2[C@H](C1)[C@H](C(C(=C2C#N)N)(C#N)C#N)C3=C(C=CC(=C3)OC)OC |
Product Overview
AM-807/14146117 (CAS 459155-75-0), with molecular formula C25H27N5O4 and molecular weight 461.21 g/mol. IUPAC: tert-butyl (8R,8aR)-6-amino-5,7,7-tricyano-8-(2,5-dimethoxyphenyl)-1,3,8,8a-tetrahydroisoquinoline-2-carboxylate.
Chemical Property Profile of AM-807/14146117
Property Insights of AM-807/14146117
The XLogP value of 3.36424 indicates that AM-807/14146117 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 145.39 Ų indicates high polarity, suggesting AM-807/14146117 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, AM-807/14146117 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AM-807/14146117?
The CAS number of AM-807/14146117 is 459155-75-0.
What is the molecular formula of AM-807/14146117?
The molecular formula of AM-807/14146117 is C25H27N5O4.
What is the molecular weight of AM-807/14146117?
The molecular weight of AM-807/14146117 is 461.21 g/mol.
Where can I buy AM-807/14146117?
You can request a quote for AM-807/14146117 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AM-807/14146117?
Yes, KEHONG BIO provides custom synthesis services for AM-807/14146117 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.