AM-807/12426039 structure

AM-807/12426039

TL;DR: AM-807/12426039 (CAS 459155-25-0) is a chemical compound with molecular formula C24H21N5S and molecular weight 411.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8R,8aR)-6-amino-2-(2-phenylethyl)-8-thiophen-2-yl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile

Also Known As: AM-807/12426039, 6-amino-2-(2-phenylethyl)-8-(2-thienyl)-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile, (8R,8aR)-6-amino-2-(2-phenylethyl)-8-thiophen-2-yl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile, (8R,8aR)-6-amino-2-phenethyl-8-(thiophen-2-yl)-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile, (8R,8aR)-6-amino-2-phenethyl-8-thiophen-2-yl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile

CAS: 459155-25-0
Molecular Formula C24H21N5S
Molecular Weight 411.15 g/mol
LogP 3.71614
Topological Polar Surface Area 100.63 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 411.15176
Heavy Atoms 30
Complexity 1095.0815

Chemical Identifiers

CAS Number 459155-25-0
SMILES C1C=C2[C@H](CN1CCC3=CC=CC=C3)[C@H](C(C(=C2C#N)N)(C#N)C#N)C4=CC=CS4

Product Overview

AM-807/12426039 (CAS 459155-25-0), with molecular formula C24H21N5S and molecular weight 411.15 g/mol. IUPAC: (8R,8aR)-6-amino-2-(2-phenylethyl)-8-thiophen-2-yl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AM-807/12426039

XLogP
3.71614
TPSA (Topological Polar Surface Area)
100.63
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
30
Complexity
1095.0815
Exact Mass
411.15176
Monoisotopic Mass
411.15176
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AM-807/12426039

The XLogP value of 3.71614 indicates that AM-807/12426039 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 100.63 Ų falls within the moderate polarity range, balancing permeability and solubility for AM-807/12426039. Following Lipinski's Rule of Five, AM-807/12426039 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AM-807/12426039?

The CAS number of AM-807/12426039 is 459155-25-0.

What is the molecular formula of AM-807/12426039?

The molecular formula of AM-807/12426039 is C24H21N5S.

What is the molecular weight of AM-807/12426039?

The molecular weight of AM-807/12426039 is 411.15 g/mol.

Where can I buy AM-807/12426039?

You can request a quote for AM-807/12426039 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AM-807/12426039?

Yes, KEHONG BIO provides custom synthesis services for AM-807/12426039 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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