(8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile structure

(8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile

TL;DR: (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile (CAS 459153-91-4) is a chemical compound with molecular formula C26H25N5O and molecular weight 423.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile

Also Known As: (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile, (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile

CAS: 459153-91-4
Molecular Formula C26H25N5O
Molecular Weight 423.21 g/mol
LogP 3.98374
Topological Polar Surface Area 109.86 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 423.2059
Heavy Atoms 32
Complexity 1239.6848

Chemical Identifiers

CAS Number 459153-91-4
SMILES CCCN1CC=C2[C@H](C1)[C@H](C(C(=C2C#N)N)(C#N)C#N)C3=CC=C(C4=CC=CC=C34)OC

Product Overview

(8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile (CAS 459153-91-4), with molecular formula C26H25N5O and molecular weight 423.21 g/mol. IUPAC: (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile

XLogP
3.98374
TPSA (Topological Polar Surface Area)
109.86
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
32
Complexity
1239.6848
Exact Mass
423.2059
Monoisotopic Mass
423.2059
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile

The XLogP value of 3.98374 indicates that (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 109.86 Ų falls within the moderate polarity range, balancing permeability and solubility for (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile. Following Lipinski's Rule of Five, (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile?

The CAS number of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile is 459153-91-4.

What is the molecular formula of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile?

The molecular formula of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile is C26H25N5O.

What is the molecular weight of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile?

The molecular weight of (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile is 423.21 g/mol.

Where can I buy (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile?

You can request a quote for (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile?

Yes, KEHONG BIO provides custom synthesis services for (8S,8aR)-6-amino-8-(4-methoxynaphthalen-1-yl)-2-propyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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