AF-399/15599059
TL;DR: AF-399/15599059 (CAS 459147-62-7) is a chemical compound with molecular formula C20H20F3N3O3 and molecular weight 407.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-benzoyl-6-[4-(dimethylamino)phenyl]-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one
Also Known As: AF-399/15599059, 5-BENZOYL-6-[4-(DIMETHYLAMINO)PHENYL]-4-HYDROXY-4-(TRIFLUOROMETHYL)-1,3-DIAZINAN-2-ONE, 5-benzoyl-6-[4-(dimethylamino)phenyl]-4-hydroxy-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one, 5-benzoyl-6-(4-dimethylaminophenyl)-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one, 6-[4-(dimethylamino)phenyl]-4-hydroxy-5-(phenylcarbonyl)-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one
| Molecular Formula | C20H20F3N3O3 |
|---|---|
| Molecular Weight | 407.15 g/mol |
| LogP | 2.8565 |
| Topological Polar Surface Area | 81.67 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 407.1457 |
| Heavy Atoms | 29 |
| Complexity | 900.6826 |
Chemical Identifiers
| CAS Number | 459147-62-7 |
|---|---|
| SMILES | CN(C)C1=CC=C(C=C1)C2C(C(NC(=O)N2)(C(F)(F)F)O)C(=O)C3=CC=CC=C3 |
Product Overview
AF-399/15599059 (CAS 459147-62-7), with molecular formula C20H20F3N3O3 and molecular weight 407.15 g/mol. IUPAC: 5-benzoyl-6-[4-(dimethylamino)phenyl]-4-hydroxy-4-(trifluoromethyl)-1,3-diazinan-2-one.
Chemical Property Profile of AF-399/15599059
Property Insights of AF-399/15599059
The XLogP value of 2.8565 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AF-399/15599059. The TPSA of 81.67 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/15599059. Following Lipinski's Rule of Five, AF-399/15599059 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/15599059?
The CAS number of AF-399/15599059 is 459147-62-7.
What is the molecular formula of AF-399/15599059?
The molecular formula of AF-399/15599059 is C20H20F3N3O3.
What is the molecular weight of AF-399/15599059?
The molecular weight of AF-399/15599059 is 407.15 g/mol.
Where can I buy AF-399/15599059?
You can request a quote for AF-399/15599059 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/15599059?
Yes, KEHONG BIO provides custom synthesis services for AF-399/15599059 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.