AM-807/13104328
TL;DR: AM-807/13104328 (CAS 459147-21-8) is a chemical compound with molecular formula C22H22FN5O and molecular weight 391.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,8aR)-6-amino-8-(2-fluoro-5-methoxyphenyl)-2-propan-2-yl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile
Also Known As: AM-807/13104328, 6-amino-8-(2-fluoro-5-methoxyphenyl)-2-isopropyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile, (8R,8aR)-6-amino-8-(2-fluoro-5-methoxyphenyl)-2-(propan-2-yl)-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile, (8R,8aR)-6-amino-8-(2-fluoro-5-methoxyphenyl)-2-isopropyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile, (8R,8aR)-6-amino-8-(2-fluoro-5-methoxyphenyl)-2-propan-2-yl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile
| Molecular Formula | C22H22FN5O |
|---|---|
| Molecular Weight | 391.18 g/mol |
| LogP | 2.96804 |
| Topological Polar Surface Area | 109.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 391.18085 |
| Heavy Atoms | 29 |
| Complexity | 1007.10895 |
Chemical Identifiers
| CAS Number | 459147-21-8 |
|---|---|
| SMILES | CC(C)N1CC=C2[C@H](C1)[C@H](C(C(=C2C#N)N)(C#N)C#N)C3=C(C=CC(=C3)OC)F |
Product Overview
AM-807/13104328 (CAS 459147-21-8), with molecular formula C22H22FN5O and molecular weight 391.18 g/mol. IUPAC: (8R,8aR)-6-amino-8-(2-fluoro-5-methoxyphenyl)-2-propan-2-yl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile.
Chemical Property Profile of AM-807/13104328
Property Insights of AM-807/13104328
The XLogP value of 2.96804 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AM-807/13104328. The TPSA of 109.86 Ų falls within the moderate polarity range, balancing permeability and solubility for AM-807/13104328. Following Lipinski's Rule of Five, AM-807/13104328 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AM-807/13104328?
The CAS number of AM-807/13104328 is 459147-21-8.
What is the molecular formula of AM-807/13104328?
The molecular formula of AM-807/13104328 is C22H22FN5O.
What is the molecular weight of AM-807/13104328?
The molecular weight of AM-807/13104328 is 391.18 g/mol.
Where can I buy AM-807/13104328?
You can request a quote for AM-807/13104328 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AM-807/13104328?
Yes, KEHONG BIO provides custom synthesis services for AM-807/13104328 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.