4-Fluorophenylacetyl chloride
TL;DR: 4-Fluorophenylacetyl chloride (CAS 459-14-3) is a chemical compound with molecular formula C8H6ClFO and molecular weight 172.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-fluorophenyl)acetyl chloride
Also Known As: 4-Fluorophenylacetyl chloride, 2-(4-fluorophenyl)acetyl chloride, 4-fluorophenylacetylchloride, 4-fluorophenacetyl chloride, 4-fluorobenzeneacetyl chloride
| Molecular Formula | C8H6ClFO |
|---|---|
| Molecular Weight | 172.01 g/mol |
| LogP | 2.1336 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 172.00912 |
| Heavy Atoms | 11 |
| Complexity | 255.2995 |
Chemical Identifiers
| CAS Number | 459-14-3 |
|---|---|
| SMILES | C1=CC(=CC=C1CC(=O)Cl)F |
Product Overview
4-Fluorophenylacetyl chloride (CAS 459-14-3), with molecular formula C8H6ClFO and molecular weight 172.01 g/mol. IUPAC: 2-(4-fluorophenyl)acetyl chloride.
Chemical Property Profile of 4-Fluorophenylacetyl chloride
Property Insights of 4-Fluorophenylacetyl chloride
The XLogP value of 2.1336 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Fluorophenylacetyl chloride. With a topological polar surface area (TPSA) of 17.07 Ų, 4-Fluorophenylacetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluorophenylacetyl chloride has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Fluorophenylacetyl chloride?
The CAS number of 4-Fluorophenylacetyl chloride is 459-14-3.
What is the molecular formula of 4-Fluorophenylacetyl chloride?
The molecular formula of 4-Fluorophenylacetyl chloride is C8H6ClFO.
What is the molecular weight of 4-Fluorophenylacetyl chloride?
The molecular weight of 4-Fluorophenylacetyl chloride is 172.01 g/mol.
Where can I buy 4-Fluorophenylacetyl chloride?
You can request a quote for 4-Fluorophenylacetyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Fluorophenylacetyl chloride?
Yes, KEHONG BIO provides custom synthesis services for 4-Fluorophenylacetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.