Ganstigmine structure

Ganstigmine

TL;DR: Ganstigmine (CAS 457075-21-7) is a chemical compound with molecular formula C22H27N3O3 and molecular weight 381.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(4aS,9aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazino[6,5-b]indol-6-yl] N-(2-ethylphenyl)carbamate

Also Known As: GANSTIGMINE, Ganstigmina, Ganstigmine [INN], ganstigminum, 2-ethylphenylgeneserine oxazine

CAS: 457075-21-7
Molecular Formula C22H27N3O3
Molecular Weight 381.21 g/mol
LogP 4.1606
Topological Polar Surface Area 54.04 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 3
Exact Mass 381.20523
Heavy Atoms 28
Complexity 900.34576

Chemical Identifiers

CAS Number 457075-21-7
SMILES CCC1=CC=CC=C1NC(=O)OC2=CC3=C(C=C2)N([C@@H]4[C@]3(CCN(O4)C)C)C

Product Overview

Ganstigmine (CAS 457075-21-7), with molecular formula C22H27N3O3 and molecular weight 381.21 g/mol. IUPAC: [(4aS,9aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazino[6,5-b]indol-6-yl] N-(2-ethylphenyl)carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ganstigmine

XLogP
4.1606
TPSA (Topological Polar Surface Area)
54.04
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
3
Heavy Atoms
28
Complexity
900.34576
Exact Mass
381.20523
Monoisotopic Mass
381.20523
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ganstigmine

The XLogP value of 4.1606 indicates that Ganstigmine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.04 Ų, Ganstigmine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ganstigmine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ganstigmine?

The CAS number of Ganstigmine is 457075-21-7.

What is the molecular formula of Ganstigmine?

The molecular formula of Ganstigmine is C22H27N3O3.

What is the molecular weight of Ganstigmine?

The molecular weight of Ganstigmine is 381.21 g/mol.

Where can I buy Ganstigmine?

You can request a quote for Ganstigmine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ganstigmine?

Yes, KEHONG BIO provides custom synthesis services for Ganstigmine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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