![1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea structure](/static/products/4544/454449-59-3.webp)
1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea
TL;DR: 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea (CAS 454449-59-3) is a chemical compound with molecular formula C15H12F2N4O2S and molecular weight 350.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(difluoromethoxy)phenyl]-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)thiourea
Also Known As: 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea, 1-[4-(difluoromethoxy)phenyl]-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)thiourea
| Molecular Formula | C15H12F2N4O2S |
|---|---|
| Molecular Weight | 350.06 g/mol |
| LogP | 3.2665 |
| Topological Polar Surface Area | 81.94 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 350.0649 |
| Heavy Atoms | 24 |
| Complexity | 921.1188 |
Chemical Identifiers
| CAS Number | 454449-59-3 |
|---|---|
| SMILES | C1=CC(=CC=C1NC(=S)NC2=CC3=C(C=C2)NC(=O)N3)OC(F)F |
Product Overview
1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea (CAS 454449-59-3), with molecular formula C15H12F2N4O2S and molecular weight 350.06 g/mol. IUPAC: 1-[4-(difluoromethoxy)phenyl]-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)thiourea.
Chemical Property Profile of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea
Property Insights of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea
The XLogP value of 3.2665 indicates that 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.94 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea. Following Lipinski's Rule of Five, 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea has 4 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea?
The CAS number of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea is 454449-59-3.
What is the molecular formula of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea?
The molecular formula of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea is C15H12F2N4O2S.
What is the molecular weight of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea?
The molecular weight of 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea is 350.06 g/mol.
Where can I buy 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea?
You can request a quote for 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-(Difluoromethoxy)phenyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.