Norchlorcyclizine dihydrochloride structure

Norchlorcyclizine dihydrochloride

TL;DR: Norchlorcyclizine dihydrochloride (CAS 454217-58-4) is a chemical compound with molecular formula C17H21Cl3N2 and molecular weight 358.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(4-chlorophenyl)-phenylmethyl]piperazine;dihydrochloride

Also Known As: Norchlorcyclizine HCl, Norchlorcyclizine dihydrochloride, Norchlorcyclizine hydrochloride, KST-1A9835, N-(p-Chlorobenzhydryl)piperazine dihydrochloride

CAS: 454217-58-4
Molecular Formula C17H21Cl3N2
Molecular Weight 358.08 g/mol
LogP 4.1782
Topological Polar Surface Area 15.3 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 2
Rotatable Bonds 3
Exact Mass 358.07703
Heavy Atoms 22
Complexity 277.0

Chemical Identifiers

CAS Number 454217-58-4
SMILES C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
InChIKey LBFBMRCUZCPOAO-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (5 patents) Organic Building Blocks (1 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

Norchlorcyclizine dihydrochloride (CAS 454217-58-4), with molecular formula C17H21Cl3N2 and molecular weight 358.08 g/mol. IUPAC: 1-[(4-chlorophenyl)-phenylmethyl]piperazine;dihydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Norchlorcyclizine dihydrochloride

XLogP
4.1782
TPSA (Topological Polar Surface Area)
15.3
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
22
Complexity
277.0
Exact Mass
358.07703
Monoisotopic Mass
358.07703
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Norchlorcyclizine dihydrochloride

The XLogP value of 4.1782 indicates that Norchlorcyclizine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.3 Ų, Norchlorcyclizine dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Norchlorcyclizine dihydrochloride has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Norchlorcyclizine dihydrochloride?

The CAS number of Norchlorcyclizine dihydrochloride is 454217-58-4.

What is the molecular formula of Norchlorcyclizine dihydrochloride?

The molecular formula of Norchlorcyclizine dihydrochloride is C17H21Cl3N2.

What is the molecular weight of Norchlorcyclizine dihydrochloride?

The molecular weight of Norchlorcyclizine dihydrochloride is 358.08 g/mol.

Where can I buy Norchlorcyclizine dihydrochloride?

You can request a quote for Norchlorcyclizine dihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Norchlorcyclizine dihydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Norchlorcyclizine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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