![N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide structure](/static/products/4529/452960-46-2.webp)
N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide
TL;DR: N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide (CAS 452960-46-2) is a chemical compound with molecular formula C16H14F2N2S2 and molecular weight 336.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-(difluoromethylsulfanyl)phenyl]-2,3-dihydroindole-1-carbothioamide
Also Known As: N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide, {[4-(difluoromethylthio)phenyl]amino}indolinylmethane-1-thione, N-[4-(difluoromethylsulfanyl)phenyl]-2,3-dihydroindole-1-carbothioamide
| Molecular Formula | C16H14F2N2S2 |
|---|---|
| Molecular Weight | 336.06 g/mol |
| LogP | 4.7608 |
| Topological Polar Surface Area | 15.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 336.05664 |
| Heavy Atoms | 22 |
| Complexity | 674.10095 |
Chemical Identifiers
| CAS Number | 452960-46-2 |
|---|---|
| SMILES | C1CN(C2=CC=CC=C21)C(=S)NC3=CC=C(C=C3)SC(F)F |
Product Overview
N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide (CAS 452960-46-2), with molecular formula C16H14F2N2S2 and molecular weight 336.06 g/mol. IUPAC: N-[4-(difluoromethylsulfanyl)phenyl]-2,3-dihydroindole-1-carbothioamide.
Chemical Property Profile of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide
Property Insights of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide
The XLogP value of 4.7608 indicates that N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.27 Ų, N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide?
The CAS number of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide is 452960-46-2.
What is the molecular formula of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide?
The molecular formula of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide is C16H14F2N2S2.
What is the molecular weight of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide?
The molecular weight of N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide is 336.06 g/mol.
Where can I buy N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide?
You can request a quote for N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide?
Yes, KEHONG BIO provides custom synthesis services for N-{4-[(difluoromethyl)sulfanyl]phenyl}-2,3-dihydro-1H-indole-1-carbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.