Jolkinolide A
TL;DR: Jolkinolide A (CAS 4527-49-5) is a chemical compound with molecular formula C20H26O3 and molecular weight 314.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,3R,10S,11R,16R)-5,11,15,15-tetramethyl-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadeca-4,8-dien-6-one
Also Known As: Jolkinolide A, KST-1A4891, KST-1A4892, NCI60_035894, (1S,3R,10S,11R,16R)-5,11,15,15-tetramethyl-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadeca-4,8-dien-6-one
| Molecular Formula | C20H26O3 |
|---|---|
| Molecular Weight | 314.19 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 38.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 314.1882 |
| Heavy Atoms | 23 |
| Complexity | 685.0 |
Chemical Identifiers
| CAS Number | 4527-49-5 |
|---|---|
| SMILES | CC1=C2[C@@H]3[C@]4(O3)CC[C@H]5[C@]([C@@H]4C=C2OC1=O)(CCCC5(C)C)C |
| InChIKey | OYXDHOVYZKWSRM-PHJMNMFVSA-N |
Product Overview
Jolkinolide A (CAS 4527-49-5), with molecular formula C20H26O3 and molecular weight 314.19 g/mol. IUPAC: (1S,3R,10S,11R,16R)-5,11,15,15-tetramethyl-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadeca-4,8-dien-6-one.
Chemical Property Profile of Jolkinolide A
Property Insights of Jolkinolide A
The XLogP value of 3.9 indicates that Jolkinolide A is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.8 Ų, Jolkinolide A exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Jolkinolide A has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Jolkinolide A?
The CAS number of Jolkinolide A is 4527-49-5.
What is the molecular formula of Jolkinolide A?
The molecular formula of Jolkinolide A is C20H26O3.
What is the molecular weight of Jolkinolide A?
The molecular weight of Jolkinolide A is 314.19 g/mol.
Where can I buy Jolkinolide A?
You can request a quote for Jolkinolide A directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Jolkinolide A?
Yes, KEHONG BIO provides custom synthesis services for Jolkinolide A and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.