Bis(2-isothiocyanatophenyl) sulfone structure

Bis(2-isothiocyanatophenyl) sulfone

TL;DR: Bis(2-isothiocyanatophenyl) sulfone (CAS 452-70-0) is a chemical compound with molecular formula C14H8N2O2S3 and molecular weight 331.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-isothiocyanato-2-(2-isothiocyanatophenyl)sulfonylbenzene

Also Known As: bis(2-isothiocyanatophenyl) sulfone, Isothiocyanatophenyl sulfone, 2,2'-sulfonylbis(isothiocyanatobenzene), 1,1'-sulfonylbis(2-isothiocyanatobenzene), 1-isothiocyanato-2-(2-isothiocyanatophenyl)sulfonylbenzene

CAS: 452-70-0
Molecular Formula C14H8N2O2S3
Molecular Weight 331.97 g/mol
LogP 5.5
Topological Polar Surface Area 131.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 4
Exact Mass 331.9748
Heavy Atoms 21
Complexity 513.0

Chemical Identifiers

CAS Number 452-70-0
SMILES C1=CC=C(C(=C1)N=C=S)S(=O)(=O)C2=CC=CC=C2N=C=S
InChIKey OUMDLRNQGOKXMQ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

Bis(2-isothiocyanatophenyl) sulfone (CAS 452-70-0), with molecular formula C14H8N2O2S3 and molecular weight 331.97 g/mol. IUPAC: 1-isothiocyanato-2-(2-isothiocyanatophenyl)sulfonylbenzene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Bis(2-isothiocyanatophenyl) sulfone

XLogP
5.5
TPSA (Topological Polar Surface Area)
131.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
4
Heavy Atoms
21
Complexity
513.0
Exact Mass
331.9748
Monoisotopic Mass
331.9748
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Bis(2-isothiocyanatophenyl) sulfone

The XLogP value of 5.5 indicates that Bis(2-isothiocyanatophenyl) sulfone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 131.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Bis(2-isothiocyanatophenyl) sulfone. Following Lipinski's Rule of Five, Bis(2-isothiocyanatophenyl) sulfone has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Bis(2-isothiocyanatophenyl) sulfone?

The CAS number of Bis(2-isothiocyanatophenyl) sulfone is 452-70-0.

What is the molecular formula of Bis(2-isothiocyanatophenyl) sulfone?

The molecular formula of Bis(2-isothiocyanatophenyl) sulfone is C14H8N2O2S3.

What is the molecular weight of Bis(2-isothiocyanatophenyl) sulfone?

The molecular weight of Bis(2-isothiocyanatophenyl) sulfone is 331.97 g/mol.

Where can I buy Bis(2-isothiocyanatophenyl) sulfone?

You can request a quote for Bis(2-isothiocyanatophenyl) sulfone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Bis(2-isothiocyanatophenyl) sulfone?

Yes, KEHONG BIO provides custom synthesis services for Bis(2-isothiocyanatophenyl) sulfone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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