2,5-Difluorotoluene structure

2,5-Difluorotoluene

TL;DR: 2,5-Difluorotoluene (CAS 452-67-5) is a chemical compound with molecular formula C7H6F2 and molecular weight 128.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1,4-difluoro-2-methylbenzene

Also Known As: 2,5-Difluorotoluene, 1,4-Difluoro-2-methylbenzene, 2,5-Difluorotolune, Benzene, 1,4-difluoro-2-methyl-, 2,4-Difluorotolune

CAS: 452-67-5
Molecular Formula C7H6F2
Molecular Weight 128.04 g/mol
LogP 3.1
Topological Polar Surface Area 0.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 128.04376
Heavy Atoms 9
Complexity 92.0

Chemical Identifiers

CAS Number 452-67-5
SMILES CC1=C(C=CC(=C1)F)F
InChIKey YSNVKDGEALPJGC-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Coatings & Adhesives (6 patents) Electronic Chemicals (13 patents) Heterocyclic Building Blocks (125 patents) Organic Building Blocks (51 patents) +5 more

Product Overview

2,5-Difluorotoluene (CAS 452-67-5), with molecular formula C7H6F2 and molecular weight 128.04 g/mol. IUPAC: 1,4-difluoro-2-methylbenzene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2,5-Difluorotoluene

XLogP
3.1
TPSA (Topological Polar Surface Area)
0.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
9
Complexity
92.0
Exact Mass
128.04376
Monoisotopic Mass
128.04376
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2,5-Difluorotoluene

The XLogP value of 3.1 indicates that 2,5-Difluorotoluene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 0.0 Ų, 2,5-Difluorotoluene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,5-Difluorotoluene has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2,5-Difluorotoluene?

The CAS number of 2,5-Difluorotoluene is 452-67-5.

What is the molecular formula of 2,5-Difluorotoluene?

The molecular formula of 2,5-Difluorotoluene is C7H6F2.

What is the molecular weight of 2,5-Difluorotoluene?

The molecular weight of 2,5-Difluorotoluene is 128.04 g/mol.

Where can I buy 2,5-Difluorotoluene?

You can request a quote for 2,5-Difluorotoluene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2,5-Difluorotoluene?

Yes, KEHONG BIO provides custom synthesis services for 2,5-Difluorotoluene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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