F0917-2142
TL;DR: F0917-2142 (CAS 451483-40-2) is a chemical compound with molecular formula C23H18F4N2O3S and molecular weight 478.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-2-fluoro-N-[4-(trifluoromethyl)phenyl]benzamide
Also Known As: F0917-2142, 2-fluoro-5-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)-N-[4-(trifluoromethyl)phenyl]benzamide, 5-((3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-fluoro-N-(4-(trifluoromethyl)phenyl)benzamide, 5-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-2-fluoro-N-[4-(trifluoromethyl)phenyl]benzamide, 4-fluoro-3-[N-p-(trifluoromethyl)phenylcarbamoyl]phenyl(oxo)-1,2,3,4-tetrahydro-2-isoquinolyl-lambda-sulfaniumolate
| Molecular Formula | C23H18F4N2O3S |
|---|---|
| Molecular Weight | 478.10 g/mol |
| LogP | 4.8438 |
| Topological Polar Surface Area | 66.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 478.0974 |
| Heavy Atoms | 33 |
| Complexity | 1306.027 |
Chemical Identifiers
| CAS Number | 451483-40-2 |
|---|---|
| SMILES | C1CN(CC2=CC=CC=C21)S(=O)(=O)C3=CC(=C(C=C3)F)C(=O)NC4=CC=C(C=C4)C(F)(F)F |
Product Overview
F0917-2142 (CAS 451483-40-2), with molecular formula C23H18F4N2O3S and molecular weight 478.10 g/mol. IUPAC: 5-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-2-fluoro-N-[4-(trifluoromethyl)phenyl]benzamide.
Chemical Property Profile of F0917-2142
Property Insights of F0917-2142
The XLogP value of 4.8438 indicates that F0917-2142 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for F0917-2142. Following Lipinski's Rule of Five, F0917-2142 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0917-2142?
The CAS number of F0917-2142 is 451483-40-2.
What is the molecular formula of F0917-2142?
The molecular formula of F0917-2142 is C23H18F4N2O3S.
What is the molecular weight of F0917-2142?
The molecular weight of F0917-2142 is 478.10 g/mol.
Where can I buy F0917-2142?
You can request a quote for F0917-2142 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0917-2142?
Yes, KEHONG BIO provides custom synthesis services for F0917-2142 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.