2-Chloro-6-thien-2-ylnicotinic acid structure

2-Chloro-6-thien-2-ylnicotinic acid

TL;DR: 2-Chloro-6-thien-2-ylnicotinic acid (CAS 4513-77-3) is a chemical compound with molecular formula C10H6ClNO2S and molecular weight 238.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-chloro-6-thiophen-2-ylpyridine-3-carboxylic acid

Also Known As: 2-CHLORO-6-THIEN-2-YLNICOTINIC ACID, 2-oxocyclohexanecarbonitrile, 2-Chloro-6-(thiophen-2-yl)nicotinic acid, 2-chloro-6-(2-thienyl)nicotinic acid, 2-Chloro-6-(thiophen-2-yl)nicotinicacid

CAS: 4513-77-3
Molecular Formula C10H6ClNO2S
Molecular Weight 238.98 g/mol
LogP 3.1617
Topological Polar Surface Area 50.19 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 238.98077
Heavy Atoms 15
Complexity 496.12842

Chemical Identifiers

CAS Number 4513-77-3
SMILES C1=CSC(=C1)C2=NC(=C(C=C2)C(=O)O)Cl

Product Overview

2-Chloro-6-thien-2-ylnicotinic acid (CAS 4513-77-3), with molecular formula C10H6ClNO2S and molecular weight 238.98 g/mol. IUPAC: 2-chloro-6-thiophen-2-ylpyridine-3-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-Chloro-6-thien-2-ylnicotinic acid

XLogP
3.1617
TPSA (Topological Polar Surface Area)
50.19
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
15
Complexity
496.12842
Exact Mass
238.98077
Monoisotopic Mass
238.98077
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-Chloro-6-thien-2-ylnicotinic acid

The XLogP value of 3.1617 indicates that 2-Chloro-6-thien-2-ylnicotinic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.19 Ų, 2-Chloro-6-thien-2-ylnicotinic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-6-thien-2-ylnicotinic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-Chloro-6-thien-2-ylnicotinic acid?

The CAS number of 2-Chloro-6-thien-2-ylnicotinic acid is 4513-77-3.

What is the molecular formula of 2-Chloro-6-thien-2-ylnicotinic acid?

The molecular formula of 2-Chloro-6-thien-2-ylnicotinic acid is C10H6ClNO2S.

What is the molecular weight of 2-Chloro-6-thien-2-ylnicotinic acid?

The molecular weight of 2-Chloro-6-thien-2-ylnicotinic acid is 238.98 g/mol.

Where can I buy 2-Chloro-6-thien-2-ylnicotinic acid?

You can request a quote for 2-Chloro-6-thien-2-ylnicotinic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-Chloro-6-thien-2-ylnicotinic acid?

Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-6-thien-2-ylnicotinic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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