F0760-1252
TL;DR: F0760-1252 (CAS 450353-16-9) is a chemical compound with molecular formula C20H15N3O3S and molecular weight 377.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-3-(4-methoxyanilino)prop-2-enenitrile
Also Known As: F0760-1252, (2E)-2-[4-(2H-1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-3-[(4-methoxyphenyl)amino]prop-2-enenitrile, (E)-2-(4-(benzo[d][1,3]dioxol-5-yl)thiazol-2-yl)-3-((4-methoxyphenyl)amino)acrylonitrile, (E)-2-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-3-(4-methoxyanilino)prop-2-enenitrile, (2E)-2-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-3-[(4-methoxyphenyl)amino]prop-2-enenitrile
| Molecular Formula | C20H15N3O3S |
|---|---|
| Molecular Weight | 377.08 g/mol |
| LogP | 4.52398 |
| Topological Polar Surface Area | 76.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 377.0834 |
| Heavy Atoms | 27 |
| Complexity | 1035.3706 |
Chemical Identifiers
| CAS Number | 450353-16-9 |
|---|---|
| SMILES | COC1=CC=C(C=C1)N/C=C(\C#N)/C2=NC(=CS2)C3=CC4=C(C=C3)OCO4 |
Product Overview
F0760-1252 (CAS 450353-16-9), with molecular formula C20H15N3O3S and molecular weight 377.08 g/mol. IUPAC: (E)-2-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-3-(4-methoxyanilino)prop-2-enenitrile.
Chemical Property Profile of F0760-1252
Property Insights of F0760-1252
The XLogP value of 4.52398 indicates that F0760-1252 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.4 Ų falls within the moderate polarity range, balancing permeability and solubility for F0760-1252. Following Lipinski's Rule of Five, F0760-1252 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0760-1252?
The CAS number of F0760-1252 is 450353-16-9.
What is the molecular formula of F0760-1252?
The molecular formula of F0760-1252 is C20H15N3O3S.
What is the molecular weight of F0760-1252?
The molecular weight of F0760-1252 is 377.08 g/mol.
Where can I buy F0760-1252?
You can request a quote for F0760-1252 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0760-1252?
Yes, KEHONG BIO provides custom synthesis services for F0760-1252 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.