1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone structure

1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone

TL;DR: 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone (CAS 450345-91-2) is a chemical compound with molecular formula C16H18N6O3 and molecular weight 342.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[4-[4-(6-amino-5-nitropyrimidin-4-yl)piperazin-1-yl]phenyl]ethanone

Also Known As: F0543-0249, 1-(4-(4-(6-amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone, 1-{4-[4-(6-amino-5-nitropyrimidin-4-yl)piperazin-1-yl]phenyl}ethan-1-one, 1-[4-[4-(6-amino-5-nitropyrimidin-4-yl)piperazin-1-yl]phenyl]ethanone, 1-{4-[4-(6-amino-5-nitropyrimidin-4-yl)piperazin-1-yl]phenyl}ethanone

CAS: 450345-91-2
Molecular Formula C16H18N6O3
Molecular Weight 342.14 g/mol
LogP 1.4962
Topological Polar Surface Area 118.49 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 8
Rotatable Bonds 4
Exact Mass 342.14404
Heavy Atoms 25
Complexity 800.0174

Chemical Identifiers

CAS Number 450345-91-2
SMILES CC(=O)C1=CC=C(C=C1)N2CCN(CC2)C3=NC=NC(=C3[N+](=O)[O-])N

Product Overview

1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone (CAS 450345-91-2), with molecular formula C16H18N6O3 and molecular weight 342.14 g/mol. IUPAC: 1-[4-[4-(6-amino-5-nitropyrimidin-4-yl)piperazin-1-yl]phenyl]ethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone

XLogP
1.4962
TPSA (Topological Polar Surface Area)
118.49
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
8
Rotatable Bonds
4
Heavy Atoms
25
Complexity
800.0174
Exact Mass
342.14404
Monoisotopic Mass
342.14404
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone

The XLogP value of 1.4962 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone. The TPSA of 118.49 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone. Following Lipinski's Rule of Five, 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone?

The CAS number of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone is 450345-91-2.

What is the molecular formula of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone?

The molecular formula of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone is C16H18N6O3.

What is the molecular weight of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone?

The molecular weight of 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone is 342.14 g/mol.

Where can I buy 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone?

You can request a quote for 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone?

Yes, KEHONG BIO provides custom synthesis services for 1-(4-(4-(6-Amino-5-nitropyrimidin-4-yl)piperazin-1-yl)phenyl)ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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