F0541-1287
TL;DR: F0541-1287 (CAS 450340-87-1) is a chemical compound with molecular formula C18H12ClF2N3OS and molecular weight 391.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-(3-chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2,6-difluorobenzamide
Also Known As: F0541-1287, N-(2-(3-chlorophenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2,6-difluorobenzamide, N-[2-(3-chlorophenyl)-2H,4H,6H-thieno[3,4-c]pyrazol-3-yl]-2,6-difluorobenzamide, N-[2-(3-chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2,6-difluorobenzamide
| Molecular Formula | C18H12ClF2N3OS |
|---|---|
| Molecular Weight | 391.04 g/mol |
| LogP | 4.803 |
| Topological Polar Surface Area | 46.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 391.03577 |
| Heavy Atoms | 26 |
| Complexity | 1001.41595 |
Chemical Identifiers
| CAS Number | 450340-87-1 |
|---|---|
| SMILES | C1C2=C(N(N=C2CS1)C3=CC(=CC=C3)Cl)NC(=O)C4=C(C=CC=C4F)F |
Product Overview
F0541-1287 (CAS 450340-87-1), with molecular formula C18H12ClF2N3OS and molecular weight 391.04 g/mol. IUPAC: N-[2-(3-chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2,6-difluorobenzamide.
Chemical Property Profile of F0541-1287
Property Insights of F0541-1287
The XLogP value of 4.803 indicates that F0541-1287 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.92 Ų, F0541-1287 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F0541-1287 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0541-1287?
The CAS number of F0541-1287 is 450340-87-1.
What is the molecular formula of F0541-1287?
The molecular formula of F0541-1287 is C18H12ClF2N3OS.
What is the molecular weight of F0541-1287?
The molecular weight of F0541-1287 is 391.04 g/mol.
Where can I buy F0541-1287?
You can request a quote for F0541-1287 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0541-1287?
Yes, KEHONG BIO provides custom synthesis services for F0541-1287 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.