![3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide structure](/static/products/4503/450-33-9.webp)
3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide
TL;DR: 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide (CAS 450-33-9) is a chemical compound with molecular formula C18H12F3NO2 and molecular weight 331.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-hydroxy-N-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide
Also Known As: 3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-naphthamide, 3-hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide, AN-153/12400001, 3-hydroxy-N-(3-(trifluoromethyl)phenyl)-2-naphthamide, alpha, alpha, alpha-Trifluoro-3-hydroxy-2-naphtho-m-toluidide
| Molecular Formula | C18H12F3NO2 |
|---|---|
| Molecular Weight | 331.08 g/mol |
| LogP | 5.1 |
| Topological Polar Surface Area | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 331.082 |
| Heavy Atoms | 24 |
| Complexity | 454.0 |
Chemical Identifiers
| CAS Number | 450-33-9 |
|---|---|
| SMILES | C1=CC=C2C=C(C(=CC2=C1)C(=O)NC3=CC=CC(=C3)C(F)(F)F)O |
| InChIKey | TYINNZKCWQSFLU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide (CAS 450-33-9), with molecular formula C18H12F3NO2 and molecular weight 331.08 g/mol. IUPAC: 3-hydroxy-N-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide.
Chemical Property Profile of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide
Property Insights of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide
The XLogP value of 5.1 indicates that 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.3 Ų, 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide?
The CAS number of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide is 450-33-9.
What is the molecular formula of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide?
The molecular formula of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide is C18H12F3NO2.
What is the molecular weight of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide?
The molecular weight of 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide is 331.08 g/mol.
Where can I buy 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide?
You can request a quote for 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 3-Hydroxy-n-[3-(trifluoromethyl)phenyl]naphthalene-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.