TH311 structure

TH311

TL;DR: TH311 (CAS 449786-54-3) is a chemical compound with molecular formula C24H24ClN3O3S and molecular weight 469.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-chlorophenyl)-N-[2-(2-methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide

Also Known As: TH311, F0541-0286, 1-(4-chlorophenyl)-N-(5,5-dioxido-2-(o-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)cyclopentanecarboxamide, 1-(4-chlorophenyl)-N-[2-(2-methylphenyl)-5,5-dioxo-2H,4H,6H-5lambda6-thieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, 1-(4-chlorophenyl)-N-[2-(2-methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide

CAS: 449786-54-3
Molecular Formula C24H24ClN3O3S
Molecular Weight 469.12 g/mol
LogP 4.71302
Topological Polar Surface Area 81.06 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 469.12268
Heavy Atoms 32
Complexity 1306.7574

Chemical Identifiers

CAS Number 449786-54-3
SMILES CC1=CC=CC=C1N2C(=C3CS(=O)(=O)CC3=N2)NC(=O)C4(CCCC4)C5=CC=C(C=C5)Cl

Product Overview

TH311 (CAS 449786-54-3), with molecular formula C24H24ClN3O3S and molecular weight 469.12 g/mol. IUPAC: 1-(4-chlorophenyl)-N-[2-(2-methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of TH311

XLogP
4.71302
TPSA (Topological Polar Surface Area)
81.06
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
32
Complexity
1306.7574
Exact Mass
469.12268
Monoisotopic Mass
469.12268
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of TH311

The XLogP value of 4.71302 indicates that TH311 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.06 Ų falls within the moderate polarity range, balancing permeability and solubility for TH311. Following Lipinski's Rule of Five, TH311 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of TH311?

The CAS number of TH311 is 449786-54-3.

What is the molecular formula of TH311?

The molecular formula of TH311 is C24H24ClN3O3S.

What is the molecular weight of TH311?

The molecular weight of TH311 is 469.12 g/mol.

Where can I buy TH311?

You can request a quote for TH311 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for TH311?

Yes, KEHONG BIO provides custom synthesis services for TH311 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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