![(3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one structure](/static/products/4492/449212-37-7.webp)
(3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one
TL;DR: (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one (CAS 449212-37-7) is a chemical compound with molecular formula C14H7Cl2N3OS and molecular weight 334.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3E)-4-chloro-3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-1H-indol-2-one
Also Known As: (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one, (3E)-4-chloro-3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-1H-indol-2-one, (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-1,3-dihydro-2H-indol-2-one
| Molecular Formula | C14H7Cl2N3OS |
|---|---|
| Molecular Weight | 334.97 g/mol |
| LogP | 4.1953 |
| Topological Polar Surface Area | 46.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 334.9687 |
| Heavy Atoms | 21 |
| Complexity | 925.5919 |
Chemical Identifiers
| CAS Number | 449212-37-7 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)Cl)/C(=C\C3=C(N=C4N3C=CS4)Cl)/C(=O)N2 |
Product Overview
(3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one (CAS 449212-37-7), with molecular formula C14H7Cl2N3OS and molecular weight 334.97 g/mol. IUPAC: (3E)-4-chloro-3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-1H-indol-2-one.
Chemical Property Profile of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one
Property Insights of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one
The XLogP value of 4.1953 indicates that (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.4 Ų, (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one?
The CAS number of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one is 449212-37-7.
What is the molecular formula of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one?
The molecular formula of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one is C14H7Cl2N3OS.
What is the molecular weight of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one?
The molecular weight of (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one is 334.97 g/mol.
Where can I buy (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one?
You can request a quote for (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for (3E)-4-Chloro-3-[(6-chloroimidazo[2,1-b]thiazol-5-yl)methylene]-1,3-dihydro-2H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.