(E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one
TL;DR: (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one (CAS 448910-98-3) is a chemical compound with molecular formula C23H23N3O2 and molecular weight 373.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(E)-2-(1,2-dimethylindol-3-yl)ethenyl]-3-(3-hydroxypropyl)quinazolin-4-one
Also Known As: (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one, 2-[(E)-2-(1,2-dimethyl-1H-indol-3-yl)ethenyl]-3-(3-hydroxypropyl)quinazolin-4(3H)-one, 2-[(E)-2-(1,2-dimethylindol-3-yl)ethenyl]-3-(3-hydroxypropyl)quinazolin-4-one, 2-[(1E)-2-(1,2-DIMETHYL-1H-INDOL-3-YL)ETHENYL]-3-(3-HYDROXYPROPYL)-3,4-DIHYDROQUINAZOLIN-4-ONE
| Molecular Formula | C23H23N3O2 |
|---|---|
| Molecular Weight | 373.18 g/mol |
| LogP | 3.74942 |
| Topological Polar Surface Area | 60.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 373.17902 |
| Heavy Atoms | 28 |
| Complexity | 1248.156 |
Chemical Identifiers
| CAS Number | 448910-98-3 |
|---|---|
| SMILES | CC1=C(C2=CC=CC=C2N1C)/C=C/C3=NC4=CC=CC=C4C(=O)N3CCCO |
Product Overview
(E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one (CAS 448910-98-3), with molecular formula C23H23N3O2 and molecular weight 373.18 g/mol. IUPAC: 2-[(E)-2-(1,2-dimethylindol-3-yl)ethenyl]-3-(3-hydroxypropyl)quinazolin-4-one.
Chemical Property Profile of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one
Property Insights of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one
The XLogP value of 3.74942 indicates that (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.05 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one. Following Lipinski's Rule of Five, (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one?
The CAS number of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one is 448910-98-3.
What is the molecular formula of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one?
The molecular formula of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one is C23H23N3O2.
What is the molecular weight of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one?
The molecular weight of (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one is 373.18 g/mol.
Where can I buy (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one?
You can request a quote for (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(2-(1,2-dimethyl-1H-indol-3-yl)vinyl)-3-(3-hydroxypropyl)quinazolin-4(3H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.