Hydrochlorothiazide; irbesartan
TL;DR: Hydrochlorothiazide; irbesartan (CAS 448264-66-2) is a chemical compound with molecular formula C32H36ClN9O5S2 and molecular weight 725.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one;6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: Avalide, Karvezide, CoAprovel, Irbesartan-hydrochlorothiazide, Hydrochlorothiazide / Irbesartan
| Molecular Formula | C32H36ClN9O5S2 |
|---|---|
| Molecular Weight | 725.20 g/mol |
| LogP | 4.4261 |
| Topological Polar Surface Area | 205.49 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 8 |
| Exact Mass | 725.19696 |
| Heavy Atoms | 49 |
| Complexity | 2100.6094 |
Chemical Identifiers
| CAS Number | 448264-66-2 |
|---|---|
| SMILES | CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5.C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl |
Product Overview
Hydrochlorothiazide; irbesartan (CAS 448264-66-2), with molecular formula C32H36ClN9O5S2 and molecular weight 725.20 g/mol. IUPAC: 2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one;6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide.
Chemical Property Profile of Hydrochlorothiazide; irbesartan
Property Insights of Hydrochlorothiazide; irbesartan
The XLogP value of 4.4261 indicates that Hydrochlorothiazide; irbesartan is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 205.49 Ų indicates high polarity, suggesting Hydrochlorothiazide; irbesartan may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Hydrochlorothiazide; irbesartan has 4 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hydrochlorothiazide; irbesartan?
The CAS number of Hydrochlorothiazide; irbesartan is 448264-66-2.
What is the molecular formula of Hydrochlorothiazide; irbesartan?
The molecular formula of Hydrochlorothiazide; irbesartan is C32H36ClN9O5S2.
What is the molecular weight of Hydrochlorothiazide; irbesartan?
The molecular weight of Hydrochlorothiazide; irbesartan is 725.20 g/mol.
Where can I buy Hydrochlorothiazide; irbesartan?
You can request a quote for Hydrochlorothiazide; irbesartan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hydrochlorothiazide; irbesartan?
Yes, KEHONG BIO provides custom synthesis services for Hydrochlorothiazide; irbesartan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.